The LDH virus: an interfering biological contaminant
نویسندگان
چکیده
منابع مشابه
Induction and biological properties of defective interfering particles of rabies virus.
A method for obtaining large quantities of defective interfering (DI) rabies virus particles that fulfill all the criteria delineated by Huang and Baltimore (1970) is described. The purified rabies DI virion was found to be much shorter (60 to 80 nm) than the complete virion (180 nm) and to have a viral genome of about half the size of normal rabies RNA but with all of the structural proteins o...
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www.thelancet.com Vol 388 August 13, 2016 659 and biological immunomodulatory drugs, and individuals with HIV (in whom, for example, the increased risk of oro-ano-genital cancer is well recognised). An opportunity is being lost to mitigate the prospective impact of HPV disease in these future patients by not currently vaccinating prepubescent boys. Second, there is unexploited scope for post-ex...
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Satellite RNAs (satRNAs) are sub-viral agents that may interact with their cognate helper virus (HV) and host plant synergistically and/or antagonistically. SatRNAs totally depend on the HV for replication, so satRNAs and HV usually evolve similar secondary or tertiary RNA structures that are recognized by a replication complex, although satRNAs and HV do not share an appreciable sequence homol...
متن کاملDefective interfering virus particles modulate virulence.
To determine whether defective interfering (DI) particles modulate virulence by initiating a cyclic pattern of virus growth in vivo, adult mice were infected with vesicular stomatitis virus (VSV), both with and without DI particles. A total of 184 mice divided into groups were inoculated intranasally. A majority of mice inoculated only with standard VSV developed paralysis, most of them between...
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A multiplicity-dependent interference was observed in respiratory syncytial virus preparations (Randall strain) grown in HEp-2 cells, and the factor mediating this interference was characterized. Cloned virus did not demonstrate this multiplicity-dependent interference, but its replication was shown to be inhibited by the interfering factor by assays of reduction of infectious yield assay, the ...
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ژورنال
عنوان ژورنال: Science
سال: 1978
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.263259